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    In the next week, blinky seizures will overwhelm Preston each afternoon. A week after that, Ana will write on Facebook, “Preston started a new ratio oil yesterday higher THC, today only being on it for the second day we saw 70-80 percent seizure reduction!!! BAM!!!! Bite that seizures!!!!” And then a week after that, Preston will have three grand mals in a day. A roller coaster, Ana will call it.
    Ana and Preston head off to school
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    No agency thoroughly regulates the treatment providers, beyond basic licensing. No rules govern the right formulation or dosage of the marijuana extract at the core of the treatment. No studies conclusively document the side effects.
    “He needs to learn to take it!” Ana says.
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    CBD is one of more than 80 active cannabinoid chemicals in the marijuana plant.ii Unlike the main psychoactive cannabinoid in marijuana, tetrahydrocannabinol (THC), CBD does not produce euphoria or intoxication.iii,iv,v Cannabinoids have their effect mainly by interacting with specific receptors on cells in the brain and body: the CB1 receptor, found on neurons and glial cells in various parts of the brain, and the CB2 receptor, found mainly in the body’s immune system. The euphoric effects of THC are caused by its activation of CB1 receptors. CBD has a very low affinity for these receptors (100 fold less than THC) and when it binds it produces little to no effect. There is also growing evidence that CBD acts on other brain signaling systems, and that these actions may be important contributors to its therapeutic effects.ii
    July 12 Preston watches as Ana and her mother, Milly Raynor, argue over how to administer the CBD oil after Preston spit out their first attempt at giving it to him orally. Milly will not let the argument end, and in the tension of the moment Ana asks, “Why did we even come down here? He needs to take it.”
    Milly walks out of the room, saying they should try later.
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    Ana is tight beside Preston
    Ana Watson has decided to try adding THC
    “Open up,” Ana coos.
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    October 8 Andrew Tobey waits for Cody Morehead to catch up as they hang the drying poles during the Realm of Caring hemp harvest in eastern Colorado.
    While there is research *****pport that medical marijuana and cannabis oil can improve the quality of life for cancer patients, not as much is known about if hemp oil cures cancer or not. If you search online for if hemp oil cures cancer, you’ll find one story after another of individuals who were diagnosed with cancer, started a treatment plan that included cannabis oil, and found that their cancer had disappeared much faster than anticipated. Not enough human research studies have been done on the subject of hemp oil and cancer to make a firm statement about the benefits of hemp oil with cancer, but there are various facts that make the connection promising and positive, and there are definitely reasons to increase the number of studies that explore if cannabis oil cures cancer.
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    “He needs to learn to take it!” Ana says.
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    But no one knows more than anecdotes because Colorado does not track how many families come to treat their children with medical marijuana — although it’s in the low hundreds — or where they go.
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