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Preparation of Etoposide is described in US patent 3,524,844 and also in Journal of Medicinal Chemistry article referenced as J. Med. Chem. 14, 936 (1971).
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Etoposide, or VP-16, is a member of a class of compounds known as epipodophyllotoxins. Etoposide exerts its antineoplastic effect by stimulating DNA-topoisomerase II ...
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