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    Step 4: The Colorado Department of Pubic Health and Environment will review the application. The department typically takes about five weeks to issue a medical marijuana card. Incomplete applications are rejected, and parents have 60 days to fix the mistakes. If an application is denied, parents must wait six months before reapplying.
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    Fortunately this ignorance is breaking down fast, and with it the madness of reefer madness. CBD is becoming a household name thanks to the likes of Charlotte Figi. CBD has been shown to fight chronic pain, spasticity, seizures, cancer and anxiety. It is a remarkably multi-purpose, non-toxic, natural substance that will soon be in everyone’s vocabulary and in every smart person’s medicine cabinet.
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    “It’s OK,” Milly whispered again. “It’s OK.”
    October 26 Preston has been eyeing his sister’s bike for a long time, taking every chance to sit on it when he could. On his 13th birthday, he finally has one of his own, with big training wheels.
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    Overall cost varies based on the amount a child takes, which itself varies based on how big the child is. Different providers also charge different prices. For kids using Charlotte’s Web, a typical family spends about $300 a month for CBD oil.
    August 5 Preston hides from his mom as she mixes his medications. He has started using THC with CBD and, aside from being playful with his mother, watched most of “Ghostbusters II.”
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    CBD is one of more than 80 active cannabinoid chemicals in the marijuana plant.ii Unlike the main psychoactive cannabinoid in marijuana, tetrahydrocannabinol (THC), CBD does not produce euphoria or intoxication.iii,iv,v Cannabinoids have their effect mainly by interacting with specific receptors on cells in the brain and body: the CB1 receptor, found on neurons and glial cells in various parts of the brain, and the CB2 receptor, found mainly in the body’s immune system. The euphoric effects of THC are caused by its activation of CB1 receptors. CBD has a very low affinity for these receptors (100 fold less than THC) and when it binds it produces little to no effect. There is also growing evidence that CBD acts on other brain signaling systems, and that these actions may be important contributors to its therapeutic effects.ii
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    It’s not just that parents are taking a gamble by moving to Colorado. It’s that they don’t even know the odds.
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    But now Maa wonders whether families who tried CBD with little success quit using the treatment before they could be included in the study. The Realm of Caring says only one patient had stopped using CBD at the time the survey was conducted. Maa is working on a genetic study trying to determine why some kids respond to CBD and some don’t.
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