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    Step 4: The Colorado Department of Pubic Health and Environment will review the application. The department typically takes about five weeks to issue a medical marijuana card. Incomplete applications are rejected, and parents have 60 days to fix the mistakes. If an application is denied, parents must wait six months before reapplying.
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    Her bookshelf at home charted the journey and spoke to her struggle. First came “What to Expect in the First Year.” Then “Keeping Faith.” Then “Delmar’s Drug Reference for Health Care Professionals.” Then “Three Weeks to Say Goodbye.”
    Smaller numbers of children in California and other states have also begun to use marijuana to treat seizures. But what makes Colorado the epicenter is the state’s large medical marijuana system, which allows for kids to be registered patients; the growing community of families with sick children; and the feedback loop of publicity that surrounds the treatment. Every happy story about a family seeing success with cannabis in Colorado pushes another family to move here.
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    A San Diego company is producing and selling what could be a legal alternative to medical marijuana.
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    It was subtle. But Ana swore there was a change in her son. He was more talkative, more stable on his feet.
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    To Ana, it sometimes seemed as if what epilepsy didn’t take from her son, the drugs would. But she also knew that just one year of uncontrolled seizures meant a 1 percent chance of dying. The longer Preston’s seizures ran riot, the likelier epilepsy would kill him.
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    “He is quite capable of going into a seizure that is basically all the time — all day and all night,” Greenwood said.
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    Some epilepsies respond well to generalized anti-seizure drugs. But the specific genetic mutation of each Dravet patient is different, meaning what works for some won’t work for others. Preston has at least four different kinds of seizure types, and they varied in severity and frequency as he grew older.
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    “OK,” Ana says as she fills the capsules. “It’s not going to be pretty.”
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