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October 8 Horticulturist Penn Mattison cuts down stubby round cannabis plants during the Realm of Caring hemp harvest. The Stanley brothers planted 17 acres of marijuana strains with below 0.3 percent THC. The plants qualify as hemp under Colorado’s laws for marijuana legalization.
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April 15 Ana Watson meets with Jason Cranford at his Rifle Mountain Dispensary grow in Boulder. Ana is visiting from North Carolina to change her residency and apply for her medical marijuana red card to use the CBD oil to try to control the seizures her son, Preston, suffers because of Dravet syndrome.
September 3 Ana is trying a new way of giving Preston his oil. She is giving him straight THC by mouth separately from the CBD oil she gives him in his feeding tube. He hated it. She squirted it in and he started spitting and sputtering as soon as he tasted it. She ended up mixing it with formula and using his feeding tube. By using the oil separately she can figure his dosing ratios for tighter control.
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The doctor continues down the list of anti-epilepsy medications, collecting the medical history of Ana’s 12-year-old son, Preston, whose seizures cause such unrelenting brain damage that he functions at the level of a 2-year-old. The doctor ticks through 13 different medicines, but Preston has already tried each one, to little effect.
“You were being a big, mean shark. It’s OK.”
May 29 Jake Beckman concentrates on splitting a plant stem for cloning. The Stanley brothers have specialized in breeding high-CBD strains of cannabis, including Charlotte’s Web.
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One of those extreme cases is out of Orange County. Blake Zika, 22, has suffered from frequent seizures since he was four years old. His illness has left him developmentally challenged.
Soon, Jason hands Ana new bottles of cannabis oil. This time, he’s giving her one bottle of high-CBD oil and another bottle containing high-THC.
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Ana Watson holds her son, Preston
“It’s a boy!” the sticker on the page proclaims.
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The hospital didn’t see any improvement in the before-and-after EEGs of four kids whose seizures appeared to lessen significantly. That may have been due to something called “electroclinical dissociation,” where the seizure still occurs but its outward indicators disappear. It also might be that parents can pick up on smaller improvements than an EEG can, said Dr. Kevin Chapman, a pediatric neurologist at Children’s who was a co-author on the study.
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So Ana visited her CBD provider, who gave her oil at a 10:1 ratio of CBD to THC, and the next day she watched as her son ate better than he had in months: a plate of fried okra, a plate of potato chips smothered in barbecue sauce, a stick of string cheese, a Frosty and, most surprising of all, tuna salad with crackers.
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